The topic of this study is Impact of Organizational Structure in Effective Management of Nigerian Organization (A study of Nigerian Brewery Plc, Enugu State. The researcher adopted the descriptive survey design. The researcher used both the primary, and secondary sources of Data in the course of the study. The primary data was sourced through the instrument of questionnaire and oral interview while secondary data was sourced through texts books, magazines, journals and internet. The Population of the study is eight hundred and ninety while the sample size is one hundred and thirty-three. The findings revealed among others that organizational structure has a great impact in the effective management of organizations. The researcher recommended among others that organizations should endeavour to have well structured organization, in order to achieve the set up objectives.